Cajanin is a potent and orally activeanti-melanogenicagent. Cajanin shows antiproliferative activity in MNT1 Cells. Cajanin efficiently decreases the melanin content. Cajanin down-regulates the mRNA and protein expression levels of MITF,tyrosinase, TRP-1 and Dct (TRP-2). Cajanin induces cell cycle arrest at G2/M and S phase. Cajanin stimulates osteoblast proliferation. Cajanin has the potential for the research of human hyperpigmented disorders and menopausal osteoporosis^[1][2].

Cajanin shows strong mitogenic as well as differentiation-promoting effects on osteoblasts^[2].
Cajanin induces the phosphorylation of both Erk1/2 and Akt^[2].

Cajanin (10 mg/kg, p.o.; daily for 30 consecutive days) increases the BMD levels in all anatomical regions of the skeleton studied in Sprague Dawley rats^[1].

300.26

C₁₆H₁₂O₆

32884-36-9

• Flavonoids
• Isoflavones

• Phenols
• Polyphenols

• Plants
• other families
• red seaweeds

• Plants
• Leguminosae

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