Levomefolic acid (5-MTHF) is an orally active, brain-penetrant natural active form of folic acid and is one of the most widely used folic acid food supplements^[1][2].

Levomefolic acid (5-MTHF) shows interaction with residues Glu406, Ile 418, Lys417 and Tyr453, of which Lys 417 and Tyr 453 play a strong physiological role in the interaction between S1 and ACE and may act as a potential inhibitor of the S1:ACE2 interaction of the SARS-CoV-2 virus^[1].
Levomefolic acid (5-MTHF) (50 nM, 72 h) increases intracellular folate metabolite activity by 7-fold better than folic acid by 2-fold in human lymphoblastoid cell line (LCL), and is a good folic acid supplement^[2].

459.46

Solid

C₂₀H₂₅N₇O₆

31690-09-2

5-甲基四氢叶酸

• Ketones, Aldehydes, Acids

Room temperature in continental US; may vary elsewhere.

H₂O : 5 mg/mL(10.88 mM;Need ultrasonic)

DMSO : 1 mg/mL(2.18 mM;Need ultrasonic)

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80℃, 6 months; -20℃, 1 month。-80℃ 储存时，请在 6 个月内使用，-20℃ 储存时，请在 1 个月内使用。