Anti-inflammatory agent 21 (compound 9o) is an orally active and low cytotoxic anti-inflammatory agent, with anIC₅₀value of 0.76 μM forNO. Anti-inflammatory agent 21 acts via accumulationROSand blocks theNF-κB/MAPKsignaling pathway. Anti-inflammatory agent 21 can ameliorate cartilage destruction and inflammatory cell infiltration in arthritis rats model^[1].

IC₅₀: 0.76 μM (NO)^[1]

424.42

C₂₄H₂₁FO₆

2408836-40-6

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.