7-Oxostaurosporine is a potent protein kinase C (PKC) inhibitor that effectively inhibits tumor growth by inducingapoptosisand inhibiting the nuclear factor (NF)-κB/p-p65 pathway^[1][2].

7-Oxostaurosporine (50 nM, 24 h)可以导致 CHO 细胞中质膜鞘磷脂增加，但不会改变神经酰胺含量^[1]。

7-Oxostaurosporin（6 mg/kg，每天一次，静脉注射）显着降低肿瘤生长，肿瘤生长抑制（TGI）为 56.1%，对体重无明显影响^[2]。

480.51

C₂₈H₂₄N₄O₄

125035-83-8

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.