GABAA receptor agent 6 (compound 2027) is a potentγ-GABAARantagonist with anK_iof 0.56 μM. GABAA receptor agent 6 shows γ-GABAAR antagonist activity with low cellular membrane permeability^[1].

K_i: 0.56 μM (γ-GABAAR)^[1]

GABAA receptor agent 6 (compound 2027) shows antagonist activity withIC₅₀s of 6.68, 1.03, 0.36, 4.13, 4.96, 2.96, 0.29, 0.59 μM for α1β2δ, α4β1δ, α4β2δ, α6β2δ, α1β2γ2, α2β2γ2, α3β2γ2, α5β2γ2 subtypes, respectively^[1].

315.41

C₁₈H₂₅N₃O₂

1808463-81-1

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.