Ceftaroline fosamil hydrate acetate is a potent cephalosporinantibiotic. Ceftaroline fosamil hydrate acetate shows broad-spectrum activity against Gram-positive pathogens, including methicillin-resistantStaphylococcus aureus(MRSA) and multidrug-resistantStreptococcus pneumoniae, and common Gram-negative organisms. Ceftaroline fosamil hydrate acetate has anti-infective activity, and can be used for the research of complicated skin and skin structure infections (cSSSIs) and community-acquiredbacterialpneumonia (CABP)^[1][2][3].

Ceftaroline fosamil hydrate acetate (s.c.) shows protective effects against experimental systemic infection caused byS. aureus N133in mice, with ED₅₀s of 1.60-2.37 mg/kg^[1].
Ceftaroline fosamil hydrate acetate (10 mg/kg; s.c.) disappeares rapidly and converts smoothly into T-91825 in blood of rats and monkeys^[1].

762.75

C₂₄H₂₇N₈O₁₁PS₄

400827-55-6

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.