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Angeli's Salt
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Angeli's Salt图片
CAS NO:13826-64-7
包装与价格：
包装价格(元)
5mg电议
10mg电议
50mg电议
100mg电议

产品介绍

A classical nitroxyl (NO-) donor

Cas No.13826-64-7
别名安吉里盐,Sodium α-oxyhyponitrite
化学名disodium diazen-1-ium-1,2,2-triolate
分子式Na2(ONNO2)
分子量122.0
溶解度H20: 50 mg/ml,PBS (pH 7.2): 50 mg/ml
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
文献引用
产品描述

Angeli’s salt is regarded as a classical nitroxyl (NO-) donor, but under certain conditions evolution of NO is also observed.1 It spontaneously dissociates in a pH-dependent, first-order process with a half-life of 2.3 minutes at 37℃ (pH 7.4) to liberate 0.54 moles of NO per mole of parent compound.[1],[2]

Reference:
[1]. Maragos, C.M., Morley, D., Wink, D.A., et al. Complexes of ·NO with nucleophiles as agents for the controlled biological release of nitric oxide. Vasorelaxant effects Journal of Medicinal Chemistry 34, 3242-3247 (1991).
[2]. Keefer, L.K., Nims, R.W., Davies, K.M., et al. “NONOates” (1-substituted diazen-1-ium-1,2-diolates) as nitric oxide donors: Convenient nitric oxide dosage forms Methods in Enzymology 268, 281-293 (1996