Methyldopa

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Methyldopa

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:	555-30-6
包装:	500mg
市场价:	400元

产品名称

甲基多巴
L-(-)-α-Methyldopa
MK-351

产品介绍

Methyldopa (L-(-)-α-Methyldopa) 是一种 α-肾上腺素能激动剂 (对α2- adrenergic receptors有选择性)。Methyldopa 是一种前药，在中枢神经系统中被代谢 (α-Methylepinephrine)。

生物活性

Methyldopa (L-(-)-α-Methyldopa), a potent antihyoertensive agent, is an alpha-adrenergic agonist (selective forα2-adrenergic receptors). Methyldopa is a prodrug and is metabolized (α-Methylepinephrine) in the central nervous system^[1]^[2].

IC₅₀& Target

α adrenergic receptor

体内研究
(In Vivo)

Methyldopa (L-(-)-α-Methyldopa; 200 mg/kg; i.p.) decreases the hyperglycemic response in the first 2 hr after Dieldrin treatment^[2].

Animal Model:	60-day-old male rats^[2]
Dosage:	200 mg/kg
Administration:	I.p.
Result:	Decreased the plasma concentration of glucose in Dieldrin-exposed rats by 24% during the 30 min following its administration.

Clinical Trial

分子量

211.21

Formula

C₁₀H₁₃NO₄

CAS 号

555-30-6

中文名称

卡比多巴EP杂质A

结构分类

Ketones, Aldehydes, Acids

来源

Plants
Hippocastanaceae
Aesculus hippocastanum

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.