Guvacine, an alkaloid found in the nut ofAreca catechu, is a potentGABA uptakpinhibitor. Guvacine inhibitsrat GAT-1,rat GAT-2andrat GAT-3withIC₅₀values of 39 μM, 58 μM and 378 μM, respectively^[1].

IC50: 39 μM (rat GAT-1), 58 μM (rat GAT-2), 378 μM (rat GAT-3), 14 μM (human GAT-1), 119 μM (huam GAT-3) and 1870 μM (human BGT-3)^[1]

127.14

C₆H₉NO₂

498-96-4

• Alkaloids
• Pyridine Alkaloids

• Plants
• Palmae
• Areca catechuL.

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.