Paeoniflorigenone

立即咨询

Paeoniflorigenone

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:	80454-42-8
包装:	1mg
市场价:	8000元

产品名称

芍药甙元酮

产品介绍

Paeoniflorigenone 是从牡丹皮中提取的一种有效成分，具有选择性诱导肿瘤细胞凋亡 (apoptosis) 和抗增殖作用。

生物活性

Paeoniflorigenone, isolated as an active ingredient from the root of moutan cortex, inducesapoptosisselectively in thecancercell lines and exhibits antiproliferative effect^[1].

体外研究
(In Vitro)

Paeoniflorigenone (0-30 μM; 0-72 hours) significantly decreases the cell proliferation of tumor cell lines and inhibits the proliferation of normal cell lines^[1].
Paeoniflorigenone (0-30 μM; 24-72 hours) significantly induces apoptotic DNA fragmentation selectively in tumor cells^[1].

Cell Proliferation Assay^[1]

Cell Line:	TIG-1, 3T3-L1, HL60, Jurkat and HeLa cells
Concentration:	0-30 μM
Incubation Time:	0-72 hours
Result:	Significantly decreased the cell proliferation of tumor cell lines and inhibited the proliferation of normal cell lines.

Apoptosis Analysis^[1]

Cell Line:	TIG-1 and 3T3-L1 (normal cells), HL60, Jurkat, and HeLa cells (tumor cells)
Concentration:	0, 1, 3, 10, 30 μM
Incubation Time:	24 and 72 hours
Result:	Induced DNA fragmentation in three tumor cell lines, but not in two normal cell lines.

分子量

318.32

性状

Oil

Formula

C₁₇H₁₈O₆

CAS 号

80454-42-8

中文名称

芍药甙元酮；芍药苷元酮

结构分类

Ketones, Aldehydes, Acids

来源

Plants
Paeoniaceae
Paeonia suffruticosaAndr.

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)