Polygalasaponin XXXI (Onjisaponin F) is an effective adjuvant for intranasal administration of influenzaInfluenza hemagglutinin(HA) vaccine to protectinfluenza virusinfection^[1].

Polygalasaponin XXXI (Onjisaponin F) also enhances anti-HA IgA and IgG Ab titers in the nasal wash, whereas Onjisaponins E and G enhances only anti-HA IgA Ab titer significantly. Polygalasaponin XXXI can induce protective immunity against intranasal infection by influenza virus^[1].
Polygalasaponin XXXI (Onjisaponin F) (1 or 10 μg/mL) also induces ChAT mRNA level in rat basal forebrain cells^[2].

Intranasal vaccination with Polygalasaponin XXXI (Onjisaponin F) inhibits proliferation of mouse adapted influenza virus A/PR/8/34 in bronchoalveolar lavages of infected mice^[1].

1589.67

Solid

C₇₅H₁₁₂O₃₆

79103-90-5

远志皂苷 F

• Terpenoids
• Triterpenes

• Plants
• Polygalaceae
• Polygala tenuifoliaWilld.

Room temperature in continental US; may vary elsewhere.

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)