| CAS NO: | 53729-52-5 |
| 包装 | 价格(元) |
| 5mg | 电议 |
| 10mg | 电议 |
| 50mg | 电议 |
| 生物活性 | Bruceantinol, a quassinoid isolated fromBrucea javanica, inhibitspepper mottle virusin pepper[1]. Bruceantinol is aSTAT3inhibitor demonstrating potent antitumor activity in in vitro and in vivo human colorectalcancer(CRC) models. Bruceantinol strongly inhibitsSTAT3DNA-binding ability (IC50=2.4 pM), blocks the constitutive and IL-6-inducedSTAT3activation, and suppresses transcription ofMCL-1, PTTG1,survivinandc-Myc[2]. | ||||||||||||
| IC50& Target | IC50: 2.4 pM (STAT3 DNA-binding ability)[2] | ||||||||||||
| 分子量 | 606.61 | ||||||||||||
| 性状 | Solid | ||||||||||||
| Formula | C30H38O13 | ||||||||||||
| CAS 号 | 53729-52-5 | ||||||||||||
| 结构分类 |
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| 来源 |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| 储存方式 |
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