VEGFR-2-IN-18 (Compound 15d) is a potentVEGFR-2inhibitor with anIC₅₀of 60 nM. VEGFR-2-IN-18 induces cellapoptosis. VEGFR-2-IN-18 shows antitumor activities^[1].

VEGFR-2-IN-18 (Compound 15d) shows antiproliferative activities with IC₅₀values of 24.10 ± 2.12, 40.90 ± 3.46, 33.40 ± 2.92 and 221.25 ± 2.55 μM against HepG2, PC3, MCF-7 and WI-38 cells, respectively^[1].

376.80

C₂₀H₁₃ClN₄O₂

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