Ramucirumab

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Ramucirumab

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

947687-13-0

包装与价格：

包装	价格(元)
1mg	电议
5mg	电议
25mg	电议
50mg	电议

产品名称

雷莫芦单抗

产品介绍

Ramucirumab 是人VEGFR-2拮抗剂，具有抗实体瘤作用。Ramucirumab 是一种人源化单克隆抗体，可与 VEGFR-2 结合，阻止 VEGFR 配体 VEGF-A，VEGF-C 和 VEGF-D 结合。Ramucirumab 也是一种血管生成抑制剂。

生物活性

Ramucirumab is a humanVEGFR-2antagonist for the treatment of solid tumors. Ramucirumab is a recombinant human immunoglobulin G1 monoclonal antibody that binds to the extracellular binding domain of VEGFR-2 and prevents the binding ofVEGFRligands:VEGF-A,VEGF-C, andVEGF-D. Ramucirumab is also an angiogenesis inhibitor^[1]^[2].

IC₅₀& Target^[1]^[2]

VEGFR-2

体外研究
(In Vitro)

Ramucirumab (10 μg/mL) impedes both VEGF- and tumor-driven cord formation^[3].
Ramucirumab does not cross react with mouse VEGFR2^[3].

Clinical Trial

分子量

143609.63

性状

Liquid

Formula

C₆₃₇₄H₉₈₆₄N₁₆₉₂O₁₉₉₆S₄₆

CAS 号

947687-13-0

中文名称

雷莫芦单抗

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.