Anticancer agent 58

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Anticancer agent 58

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

包装与价格：

包装	价格(元)
100mg	电议
250mg	电议
500mg	电议

产品介绍

Anticancer agent 58 (compound 16) 对多种癌细胞具有抑制活性，特别是在 A549 和 T24 细胞中，IC₅₀分别为 0.6 μM 和 0.7 μM。Anticancer agent 58 通过激活caspase 3/8/9活性诱导细胞凋亡 (apoptosis)，也诱导 Ca²⁺和ROS水平升高。Anticancer agent 58 在 T24 异种移植小鼠模型中能显著抑制肿瘤生长。

生物活性	Anticancer agent 58 (compound 16) has inhibitory activity against kinds ofcancercell lines, especially in A549 and T24 withIC₅₀s of 0.6 μM and 0.7 μM, respectively. Anticancer agent 58 inducesapoptosisby activatingcaspase3/8/9activity, and induces an increase of Ca²⁺andROSincancercells. Anticancer agent 58 significantly decreases mitochondrial membrane potential. Anticancer agent 58 can suppress tumor growth in T24 mouse xenograft model^[1].
IC₅₀& Target	IC₅₀: 0.6 μM in A549, 0.7 μM T24^[1]
分子量	617.86
Formula	C₃₉H₅₅NO₅
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.