[登录] [免费注册]
试剂仪器网
发布求购
位置：首页 > 产品库 > Ciprofibrate
立即咨询
咨询类型：
     
*姓名：
*电话：
*单位：
Email：
*留言内容：
请详细说明您的需求。
*验证码：
 
Ciprofibrate
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Ciprofibrate图片
CAS NO:52214-84-3
包装与价格：
包装价格(元)
10mM (in 1mL DMSO)电议
25mg电议
100mg电议
200mg电议

产品介绍
Ciprofibrate (Win35833) 是一种有效的过氧化物酶体增殖剂，可增加 PPARalpha 的磷酸化水平。
Cas No.52214-84-3
别名环丙贝特; Win35833
化学名2-(4-(2,2-dichlorocyclopropyl)phenoxy)-2-methylpropanoic acid
Canonical SMILESCC(C(O)=O)(OC1=CC=C(C2CC2(Cl)Cl)C=C1)C
分子式C13H14Cl2O3
分子量289.15
溶解度≥ 10.85 mg/mL in DMSO, ≥ 94.6 mg/mL in EtOH
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Ciprofibrate is a peroxisome proliferator-activated receptor agonist.Target: PPARCiprofibrate is a hypolipidemic compound that can induce proliferation of peroxisomes in liver cells of rats. Known to be a PPARα (peroxisome proliferator-activated receptor α) agonist [1, 2].

References:
[1]. Passilly, P., et al., Phosphorylation of peroxisome proliferator-activated receptor alpha in rat Fao cells and stimulation by ciprofibrate. Biochem Pharmacol, 1999. 58(6): p. 1001-8.
[2]. Clemencet, M.C., et al., Differences in cell proliferation in rodent and human hepatic derived cell lines exposed to ciprofibrate. Cancer Lett, 2005. 222(2): p. 217-26.