Rosiglitazone (BRL 49653) hydrochloride 是一种具有口服活性的选择性 PPARγ；激动剂（EC50:60 nM，Kd:40 nM）。
| Cas No. | 302543-62-0 |
| 别名 | 盐酸罗格列酮; BRL 49653 hydrochloride |
| 化学名 | 5-(4-(2-(methyl(pyridin-2-yl)amino)ethoxy)benzyl)thiazolidine-2,4-dione hydrochloride |
| Canonical SMILES | CN(C1=CC=CC=N1)CCOC2=CC=C(CC3C(NC(S3)=O)=O)C=C2.Cl |
| 分子式 | C18H20ClN3O3S |
| 分子量 | 393.89 |
| 溶解度 | ≥ 39.4 mg/mL in DMSO, ≥ 51.2 mg/mL in EtOH with ultrasonic, ≥ 2.81 mg/mL in Water with ultrasonic and warming |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Rosiglitazone is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells. |
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