Calcium 2-oxoglutarate is an intermediate in the production of ATP or GTP in the Krebs cycle. Calcium 2-oxoglutarate also acts as the major carbon skeleton for nitrogen-assimilatory reactions. Calcium 2-oxoglutarate is a reversible inhibitor oftyrosinase(IC₅₀=15 mM)^[1][2].

Calcium 2-oxoglutarate has other physiological capabilities including reduction of ammonia level formed in the lung and general ammonia detoxification, protective role against lipid peroxidation and neuroprotective effect against cyanide poisoning^[1].
Calcium 2-oxoglutarate acts as precursor for the synthesis of amino acids and nucleotides^[2].

184.16

C₅H₄CaO₅

71686-01-6

• Ketones, Aldehydes, Acids

Room temperature in continental US; may vary elsewhere.

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