NBD-125

立即咨询

NBD-125

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

2367641-24-3

包装与价格：

包装	价格(元)
100mg	电议
250mg	电议
500mg	电议

产品介绍

NBD-125 (B-12) 是berberine 的类似物，是RXRα的激动剂，其在KM12C 细胞中的IC₅₀值为31.10 μM。

生物活性

NBD-125 (B-12), a berberine analogue, is anRXRαactivator, with anIC₅₀of 31.10 μM in KM12C cell^[1].

体外研究
(In Vitro)

NBD-125 (B-12) exhibits the strongest transcriptional activation ability to RXRα and the greatest inhibitory effect on colon cancer cell growth^[1].
NBD-125 (B-12, 0-80, μM) inhibits β-catenin signaling and cell proliferation in colon cancer cells^[1].

Western Blot Analysis^[1]

Cell Line:	Km12c, HCT116 and SW620 cell lines.
Concentration:	0-50 μM, 0-60, 0-80 μM.
Incubation Time:	15 h.
Result:	Downregulated c-Myc, Cdc42 protein levels.

分子量

327.80

Formula

C₁₉H₁₈ClNO₂

CAS 号

2367641-24-3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.