IDO1-IN-15 is a potentIDO1inhibitor (IC₅₀=127 nM). IDO1-IN-15 has comparable potency againstIDO1enzyme in vitro with Epacadostat^[1].

Cas9-IN-2 is a potentCas9inhibitor (IC₅₀=246 μM), Cas9-IN-2 acts by binding to apo-Cas9 to prevent Cas9:gRNA complex formation, which can potentially be applied to modulate and control Cas9 activity in various applications^[1].

401.19

C₁₃H₁₄BrFN₆O₃

2126853-17-4

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