TLR7/8 antagonist 2

立即咨询

TLR7/8 antagonist 2

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

包装与价格：

包装	价格(元)
100mg	电议
250mg	电议
500mg	电议

产品介绍

TLR7/8 antagonist 2 (Compound 15) 是一种有效的、具有口服活性的TLR7/8激动剂，IC₅₀值分别为 4.9 和 0.6 nM。TLR7 和 TLR8 的不适当激活与几种自身免疫性疾病有关，例如红斑狼疮。TLR7/8 antagonist 2 具有自身免疫性疾病研究的潜力。

生物活性	TLR7/8 antagonist 2 (Compound 15) is a potent and orally active agonist ofTLR7/8withIC₅₀s of 4.9 and 0.6 nM, respectively. Inappropriate activation ofTLR7andTLR8is linked to several autoimmune diseases, such as lupus erythematosus. TLR7/8 antagonist 2 has the potential for the research of autoimmune diseases^[1].
分子量	379.47
Formula	C₂₂H₂₆FN₅
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.