KRAS G12C inhibitor 5 is aKRas G12Cinhibitor extracted from patent WO2017201161A1, Compound example 147^[1].

Kirsten Rat Sarcoma 2 Viral Oncogene Homolog (KRas) is a small GTPase and a member of the Ras family of oncogenes. KRas serves a molecular switch cycling between inactive (GDP -bound) and active (GTP -bound) states to transduce upstream cellular signals received from multiple tyrosine kinases to downstream effectors to regulate a wide variety of processes, including cellular proliferation^[1].

551.68

C₃₂H₃₇N₇O₂

2158297-63-1

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.