Phyllomedusin, an tachykinin decapeptide, is aNK1receptoragonist. Phyllomedusin has vasodilating activity and provokes the contraction of the pylorus^[1][2][3].

Phyllomedusin increases neuronal excitation with psychoactive and behavioral responses^[4].
Phyllomedusin can cause smooth muscle contraction and vasodilatation^[4].

Phyllomedusin (30-300 μg/kg, i.p.) delays gastric emptying in conscious rats^[2].
Phyllomedusin (0.1 and 5 μg/kg, i.v.) has stimulant activity on the stomach of the anaesthetized rat^[3].

1171.37

C₅₂H₈₂N₁₆O₁₃S

26145-48-2

{Pyr}-NPNRFIGLM-NH2

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