Neurokinin A (4-10) TFA is atachykinin NK₂receptoragonist^[1].

NK₂receptor^[1]

Neurokinin A (NKA) and its truncated form NKA(4-10) are potent spasmogens of human colon circular muscle, an action mediated exclusively via tachykinin NK₂receptors. A structure-activity study of the neurokinin A (NKA) fragment NKA(4-10) is performed to investigate the importance of amino acid residues for receptor efficacy, potency and affinity at the NK₂receptor in human colon circular muscle. A high density of NK₂receptors has been demonstrated in this tissue, using in vitro autoradiography and radioligand binding^[1].

880.93

Solid

C₃₆H₅₅F₃N₈O₁₂S

Asp-Ser-Phe-Val-Gly-Leu-Met-NH2

DSFVGLM-NH2

Room temperature in continental US; may vary elsewhere.

Sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

H₂O :< 0.1 mg/mL(insoluble)