JKC363, a selectivemelanocortin MC4 receptorantagonist, has a 90-fold higher affinity at the MC4 receptor (IC₅₀=0.5 nM) than at the MC3 receptor (44.9 nM). JKC-363 blocks the stimulatory effect of α-MSH on TRH release. Anti-hyperalgesic effect^[1][2].

1506.71

C₆₉H₉₁N₁₉O₁₆S₂

436083-30-6

{Mpa}-EH-{D-2-Nal}-RWGCPPKD (Disulfide bridge:Mpa1-Cys8)

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.