| CAS NO: | 17210-51-4 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
| Cas No. | 17210-51-4 |
| 别名 | 氢溴酸胍喹啉,Norarecoline |
| 化学名 | 1,2,5,6-tetrahydro-3-pyridinecarboxylic acid, methyl ester, monohydrobromide |
| Canonical SMILES | O=C(OC)C1=CCCNC1.Br |
| 分子式 | C7H11NO2o HBr |
| 分子量 | 222.1 |
| 溶解度 | ≤1mg/ml in DMSO;1mg/ml in dimethyl formamide |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Target: atrial and ileal muscarinic receptors IC50: 2.1 mM for growth inhibition of human buccal epithelial cells Guvacoline is a kind of natural alkaloid which is found in areca nuts that is related to the nootropic, arecoline. Guvacoline can function as a full agonist of atrial and ileal muscarinic receptors. In Vitro: In human buccal epithelial cells, Guvacoline could significantly decrease the colony-formation efficiency in a dose dependent manner, with the IC50 value of 2.1 mM. Besides, Guvacoline could also dose-dependently reduce the amount of total free low-molecular-weight thiols (0.88 mM Guvacoline caused 25% decrease) and increase the number of single strand breaks [1]. In Vivo: No data available recently. Clinical trial: No data available recently. Reference: |
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