H2L 5765834 is an antagonist oflysophosphatidic acid receptors LPA₁,LPA₃, andLPA₅, withIC₅₀s of 94, 752, and 463 nM respectively^[1].

H2L 5765834 displays no effect on LPA₂or LPA₄receptors^[1].
H2L 5765834 inhibits LPA-induced platelet shape change with an IC₅₀of 13.73±2.52 μM^[1].

H2L 5765834 (20 mg/kg; i.p.) could not affect the LPA-induced decrease of alanine transaminase (ALT) in the acetaminophen (APAP) overdose-induced acute liver injury model^[2].

404.33

Solid

C₂₁H₁₂N₂O₇

420841-84-5

Room temperature in continental US; may vary elsewhere.

DMSO : 250 mg/mL(618.31 mM;Need ultrasonic)

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80℃, 6 months; -20℃, 1 month。-80℃ 储存时，请在 6 个月内使用，-20℃ 储存时，请在 1 个月内使用。