LTD4 antagonist 1

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LTD4 antagonist 1

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

136564-67-5

包装与价格：

包装	价格(元)
100mg	电议
250mg	电议
500mg	电议

产品介绍

LTD₄antagonist 1 是一种有效有效的白三烯 D₄(leukotriene D₄,LTD₄) 拮抗剂，K_i值为 0.57 nM。

生物活性

LTD₄antagonist 1 is a potent, orally active antagonist ofleukotriene D₄(LTD₄) with aK_iof 0.57 nM.

IC₅₀& Target^[1]

LTD₄

0.57 nM (Ki)

体外研究
(In Vitro)

LTD₄antagonist 1 (Compound 38b) exhibits a K_iof 0.57 nM for displacement of [³H]LTD₄on guinea pig lung membranes, a pK_Bof 9.93±0.14 versus LTE₄on guinea pig trachea^[1].

体内研究
(In Vivo)

LTD₄antagonist 1 (Compound 38b) exhibits a po ED₅₀/iv ED₅₀of 1.44 and 0.036 μmol/kg in LTD₄-induced bronchoconstriction in guinea pigs^[1].

分子量

615.66

Formula

C₃₁H₃₂F₃N₃O₅S

CAS 号

136564-67-5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.