hA2A/hCA XII modulator 1 (compound 14), a triazolopirazine, is a potenthA_2A adenosine receptor (hA_2AAR)antagonist withK_is of 6.4 nM, 4.819 μM, >30 μM for hA_2AAR, hA₁AR, hA₃AR, respectively. hA2A/hCA XII modulator 1 is a potenthumancarbonic anhydraseXII (hCA XII)inhibitor withK_is of 6.2 nM, 46 nM, 466 nM, 8.351 μM for hCA XII, hCA II, hCA IX and hCA I, respectively. hA2A/hCA XII modulator 1 has the potential for cancer research^[1].

501.52

C₂₄H₁₉N₇O₄S

2548963-55-7

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.