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Sulfamerazine sodium salt
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Sulfamerazine sodium salt图片
CAS NO:127-58-2
包装:50mg
市场价:504元

产品介绍
Sulfamerazine Sodium 是一种磺胺类抗菌药物。
Cas No.127-58-2
别名磺胺甲基嘧啶钠; Soluble sulfamerazine
化学名sodium;(4-aminophenyl)sulfonyl-(4-methylpyrimidin-2-yl)azanide
Canonical SMILESCC1=NC(=NC=C1)[N-]S(=O)(=O)C2=CC=C(C=C2)N.[Na+]
分子式C11H11N4NaO2S
分子量286.29
溶解度DMF: 20 mg/ml,DMSO: 15 mg/ml,Ethanol: 1 mg/ml,PBS (pH 7.2): 5 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Sulfamerazine Sodium is a sulfonamide antibacterial.Target: AntibacterialSulfamerazine, the monomethyl derivative of sulfadiazine, is 2-sulfanilamido-4-methylpyrimidine. Sulfamerazine is a sulfonamide drug that inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA) for binding to dihydropteroate synthetase (dihydrofolate synthetase). Sulfamerazine is bacteriostatic in nature. Inhibition of dihydrofolic acid synthesis decreases the synthesis of bacterial nucleotides and DNA [1].

References:
[1]. HALL, W.H. and W.W. SPINK, Sulfamerazine: clinical evaluation in 116 cases. Journal of the American Medical Association, 1943. 123(3): p. 125-131.