Steroid sulfatase-IN-1

立即咨询

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

2403716-19-6

包装与价格：

包装	价格(元)
100mg	电议
250mg	电议
500mg	电议

产品介绍

Steroid sulfatase-IN-1 是一种有效的且具有口服活性的Steroid sulfatase抑制剂，IC₅₀为 1.71 μM。Steroid sulfatase-IN-1 在体内发挥抗肿瘤作用 (TGI=51%)。Steroid sulfatase-IN-1 具有乳腺癌研究潜力。

生物活性

Steroid sulfatase-IN-1 is a potent and orally activeSteroid sulfataseinhibitor with anIC₅₀of 1.71 μM. Steroid sulfatase-IN-1 shows antitumor activity (TGI=51%) in vivo. Steroid sulfatase-IN-1 has the potential for the research of breastcancer^[1].

IC₅₀& Target

IC₅₀: 1.71 μM (Steroid sulfatase)^[1]

体内研究
(In Vivo)

Steroid sulfatase-IN-1 (compound 4 b) (50 mg/kg; p.o.) shows significant antitumor activity with the TGI value of 51%^[1].

Animal Model:	67NR mouse^[1]
Dosage:	50 mg/kg
Administration:	P.o.
Result:	Showed significant antitumor activity with the TGI value of 51%.

分子量

385.23

Formula

C₁₄H₁₀Cl₂N₄O₃S

CAS 号

2403716-19-6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.