CI 972 anhydrous is a potent, orally active, and competitive inhibitor ofpurine nucleoside phosphorylase (PNP)(K_i=0.83 μM) under development as a T cell-selective immunosuppressive agent^[1][2].

Ki: 0.83 μM (PNP)^[1]

CI 972 anhydrous (5-150 mg/kg; p.o.) produces dose-dependent elevation of plasma inosine one hour after administration to rats^[1].

297.76

C₁₁H₁₂ClN₅OS

115787-68-3

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.