| CAS NO: | 1580555-26-5 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| 生物活性 | Taldefgrobep alfa (BMS 986089; RG 6206; RO 7239361) is a potent inhibitory antibody targeting to humanmyostatin. Taldefgrobep alfa is a fusion protein composed of a human IgG1-Fc domain and Adnectin domain. Taldefgrobep alfa can be used for spinal muscular atrophy (SMA) research[1][2]. |
| IC50& Target | Myostatin[1] |
| 体内研究 (In Vivo) | Taldefgrobep alfa (2 mg/kg; iv or sc; single dose) 静脉注射小鼠后具有较快的血浆清除率，而皮下注射可使其被缓慢吸收 (Tmax=24 h)，Cmax为 15.4 mg/mL，生物利用度 (F) 为84%[1]。 |
| CAS 号 | 1580555-26-5 |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
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