Shishijimicin A

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Shishijimicin A

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

503860-50-2

包装与价格：

包装	价格(元)
100mg	电议
250mg	电议
500mg	电议

产品介绍

Shishijimicin A 是一种新型的抗肿瘤剂，它是从子囊菌 Didemnum proliferum 中发现的。Shishijimicin A 表现出抗肿瘤活性，具有高度的细胞毒性。

生物活性

Shishijimicin A is a novelantitumor agentfound from the Ascidian Didemnum proliferum. Shishijimicin A shows anti-tumor activity with highly potent cytotoxicities^[1]^[2].

体外研究
(In Vitro)

Shishijimicin A (compound 1) (0.47-2.0 pg/mL) shows high cytotoxicity for 3Y1, Hela and P388 cells^[1].
Shishijimicin A (0.13-1000 nM) shows high cytotoxicity for MES SA, MES SA DX and HEK 293T cells^[2].

Cell Cytotoxicity Assay^[1]

Cell Line:	3Y1, Hela and P388 cells
Concentration:	0.47-2.0 pg/mL
Incubation Time:
Result:	Showed IC₅₀values of 2.0, 1.8, and 0.47 pg/mL for 3Y1, Hela and P388 cells, respectively.

Cell Cytotoxicity Assay^[2]

Cell Line:	MES SA, MES SA DX and HEK 293T cells
Concentration:	0.13-1000 nM
Incubation Time:
Result:	Showed IC₅₀values of 0.13, >1000, and 0.016 nM for MES SA, MES SA DX and HEK 293T cells, respectively.

分子量

981.18

Formula

C₄₆H₅₂N₄O₁₂S₄

CAS 号

503860-50-2

结构分类

Alkaloids
Pyridine Alkaloids

Alkaloids
Indole Alkaloids

Others

来源

Didemnum proliferum

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.