AKR1C3-IN-6 (Compound 1) is a potent, selectiveAKR1C3inhibitor withIC₅₀values of 0.31 μM and 73.23 μM against AKR1C3 andAKR1C2, respectively. AKR1C3-IN-6 shows antitumor activity^[1].

IC₅₀: 0.31 μM (AKR1C3), 73.23 μM (AKR1C2)^[1]

AKR1C3-IN-6 (Compound 1) shows antiproliferative activity with an IC₅₀of 81.40 ± 2.29 μM against prostate cancer cell line 22rv1^[1].

392.33

C₁₈H₁₅F₃N₄O₃

2137881-54-8

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.