| CAS NO: | 564-87-4 |
| 包装: | 2mg |
| Cas No. | 564-87-4 |
| 化学名 | 11-cis-retinal |
| Canonical SMILES | CC1=C(/C=C/C(C)=C/C=C\C(C)=C\C([H])=O)C(C)(C)CCC1 |
| 分子式 | C20H28O |
| 分子量 | 284.4 |
| 溶解度 | Slightly Soluble in Chloroform, Methanol |
| 储存条件 | Store at -80℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 文献引用 | |
| 产品描述 | 11-cis Retinal is a chromophore that binds to opsin in the mammalian visual system as an inverse agonist forming the inactive conformation of rhodopsin. When 11-cis retinal absorbs a photon of light, it isomerizes to form all-trans retinal beginning the phototransduction cycle, which is the basis for mammalian vision. A G121L mutation in opsin allows 11-cis retinal to bind as a partial agonist and activate rhodopsin in the absence of light. In a moth model of carotenoid deficiency-induced low visual sensitivity, 11-cis retinal application to compound eyes restored visual sensitivity almost completely. |
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