ALK5-IN-28

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ALK5-IN-28

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

2785430-84-2

包装与价格：

包装	价格(元)
100mg	电议
250mg	电议
500mg	电议

产品介绍

ALK5-IN-28 (化合物 Ex-05) 是一种选择性的ALK-5抑制剂 (IC₅₀≤10 nM;K_i)，能抑制TGF-β诱导的SMAD信号传导。ALK5-IN-28 有抑制体内肿瘤生长的潜力。ALK5-IN-28 可用于增殖性疾病，如癌症、纤维化疾病、系统性硬化症的研究。

生物活性

ALK5-IN-28 (compound Ex-05) is a selectiveALK-5inhibitor (IC₅₀≤10 nM), inhibitsTGF-β-inducedSMADsignaling. ALK5-IN-28 has the potential to inhibit growth of tumour in vivo. ALK5-IN-28 can be used in study of proliferative diseases such ascancer, fibrotic diseases, and systemic sclerosis^[1].

IC₅₀& Target^[1]

ALK5

≤10 nM (IC₅₀)

分子量

425.53

Formula

C₂₅H₂₇N₇

CAS 号

2785430-84-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.