AZD7254

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AZD7254

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

1126366-28-6

包装与价格：

产品介绍

AZD7254 是一种具有口服活性的Smoothened (SMO)抑制剂，对 sonic Hh protein (shh) 的EC₅₀值为 1.0 nM。

生物活性	AZD7254 is an orally activeSmoothened (SMO)inhibitor with anEC₅₀of 1.0 nM against sonic Hh protein (shh)^[1].
体内研究 (In Vivo)	AZD7254 (40 mg/kg; p.o.; twice daily for 10 days) exhibits 42% tumor growth inhibition in an HT29-MEF (murine embryonic fibroblast) co-implant xenograft model^[1].
分子量	398.46
Formula	C₂₄H₂₂N₄O₂
CAS 号	1126366-28-6
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.