CRBN-6-5-5-VHL is a potent and selectivevon Hippel-Lindau-basedcereblon(CRBN) degrader with aDC₅₀value of 1.5 nM. CRBN-6-5-5-VHL has almost no effect on the degradation of the neo-substrates IKZF1 and IKZF3^[1].

972.20

Solid

C₅₁H₆₉N₇O₁₀S

2362575-45-7

Room temperature in continental US; may vary elsewhere.

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)