PROTAC IRAK4 degrader-3

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本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

2374122-43-5

包装与价格：

包装	价格(元)
100mg	电议
250mg	电议
500mg	电议

产品介绍

PROTAC IRAK4 degrader-3 是一种基于von Hippel-Lindau的IRAK4降解剂 PROTAC。

生物活性

PROTACIRAK4 degrader-3 is a PROTAC-inducedIRAK4degrader based onvon Hippel-Lindau^[1].

IC₅₀& Target^[1]

IRAK4

体外研究
(In Vitro)

PROTAC IRAK4 degrader-3 (0.01~10 μM; 2 hours; PBMCs) mediated degradation is occurring in a proteasome dependent manner^[1].
PROTAC IRAK4 degrader-3 (0.01~100 μM; 18 hours; PBMCs) is capable of completely blocking IL-6 secretion^[1].

Western Blot Analysis^[1]

Cell Line:	PBMCs
Concentration:	0.01~10 μM
Incubation Time:	2 hours
Result:	IRAK4 PROTAC-mediated degradation was occurring in a proteasome dependent manner.

分子量

1086.28

Formula

C₅₇H₆₈FN₁₁O₈S

CAS 号

2374122-43-5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.