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Polygalaxanthone III
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Polygalaxanthone III图片
CAS NO:162857-78-5
包装:20mg
市场价:2720元

产品介绍
Polygalaxanthone III 是从野生远志中提取的，对 CYP450 酶有抑制作用。
Cas No.162857-78-5
别名远志山酮III
化学名2-[(2S,3R,4R,5S,6R)-6-[[(2R,3R,4R)-3,4-dihydroxy-4-(hydroxymethyl)oxolan-2-yl]oxymethyl]-3,4,5-trihydroxyoxan-2-yl]-1,3,6-trihydroxy-7-methoxyxanthen-9-one
Canonical SMILESCOC1=C(C=C2C(=C1)C(=O)C3=C(C(=C(C=C3O2)O)C4C(C(C(C(O4)COC5C(C(CO5)(CO)O)O)O)O)O)O)O
分子式C25H28O15
分子量568.39
溶解度≥ 56.8mg/mL in DMSO with ultrasonic
储存条件4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Polygalaxanthone III is extracted from polygala tenuifolia wild, has inhibitory effect towards CYP450 enzyme. Polygalaxanthone III inhibits chlorzoxazone 6-hydroxylation catalyzed by CYP2E1 with an IC50 of 50.56 μM[1].

References:
[1]. Li ZL, et al. Effect of oligosaccharide esters and polygalaxanthone Ill from Polygala tenuifolia willd towards cytochrome P450. Zhongguo Zhong Yao Za Zhi. 2014 Nov;39(22):4459-63.