Bis-propargyl-PEG9 is aPEG-basedPROTAClinkerused in the synthesis ofPROTACs. Bis-propargyl-PEG9 can be used to synthesize the bivalentestrogen receptorligands^[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

490.58

C₂₄H₄₂O₁₀

1351373-47-1

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.