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ONO 2506
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
ONO 2506图片
CAS NO:185517-21-9
包装与价格：
包装价格(元)
10mM (in 1mL DMSO)电议
10mg电议
25mg电议
50mg电议
100mg电议

产品介绍
Arundic acid (ONO-2506) 是一种星形胶质细胞调节剂，通过抑制 S-100β 来调节星形胶质细胞的活化，从而延缓脑梗死的扩大；合成。
Cas No.185517-21-9
别名(R)-(-)-2-丙基辛酸,ONO-2506; (R)-2-Propyloctanoic acid
化学名(R)-2-propyloctanoic acid
Canonical SMILESOC([C@H](CCC)CCCCCC)=O
分子式C11H22O2
分子量186.29
溶解度<18.63mg/ml in DMSO;<18.63mg/ml in ethanol
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
文献引用
产品描述

Arundic acid (ONO-2506) is an astrocyte-modulating agent, which delays the expansion of cerebral infarcts by modulating the activation of astrocytes through inhibition of S-100β synthesis. Arundic acid (ONO-2506) has been developed as a therapeutic agent for stroke and Alzheimer’s disease[1][2][3].

References:
[1]. Tomoyuki Hasegawa, et al. Process Development of ONO-2506: A Therapeutic Agent for Stroke and Alzheimer's Disease. Org. Process Res. Dev.200372168-171.
[2]. Kato H, et al. Arundic acid, an astrocyte-modulating agent, protects dopaminergic neurons against MPTPneurotoxicity in mice. Brain Res. 2004 Dec 24;1030(1):66-73.