PKDCC抗体 产品名称 Anti-PKDCC Anti-protein kinase domain containing, cytoplasmic Antibody 产品介绍
靶标： PKDCC 产品别名： RLSDF； SGK493； Vlk； PKDCC； protein kinase domain containing, cytoplasmic； protein kinase domain containing, cytoplasmic； extracellular tyrosine-protein kinase PKDCC； protein kinase domain containing, cytoplasmic homolog； protein kinase domain-containing protein, cytoplasmic； protein kinase-like protein SgK493； sugen kinase 493； vertebrate lonesome kinase； 背景信息： VLK was identified as a novel protein kinase that was induced after the differentiation of cultured embryonic stem cells into mesendoderm. It has no homologs in invertebrates, but is highly conserved in vertebrate species although it does not belong to any known protein kinase groups. VLK is initially expressed in E-cadherin-positive anterior visceral endoderm and mesendoderm, but its expression is later confined to E-cadherin-negative mesenchyme. It is enriched in the Golgi apparatus and is thought to regulate the rate of protein export from the Golgi. Targeted disruption of VLK in mice leads to a defect in lung development and neonatal lethality. It has been suggested that mutations in VLK may be associated with the allergic condition atopy. 宿主：Rbt 用户评论 产品评分 目前评分共0人 产品质量
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