FOXRED2蛋白抗体 产品名称 Anti-FOXRED2 Anti-FAD dependent oxidoreductase domain containing 2 Antibody 产品介绍
靶标： FOXRED2 产品别名： ERFAD； FOXRED2； FAD dependent oxidoreductase domain containing 2； FAD dependent oxidoreductase domain containing 2； FAD-dependent oxidoreductase domain-containing protein 2； ER flavoprotein associated with degradation； endoplasmic reticulum flavoprotein associated with degradation； FOXRED2蛋白； 背景信息： FOXRED2, also known as ERFAD, is an endoplasmic reticulum (ER) luminal flavoprotein which may function in ER associated degradation (ERAD). It has been proposed to bind non-native proteins in the endoplasmic reticulum and target them to the ubiquitination machinery for subsequent degradation. Upon knockdown of FOXRED2, the degradation of the ERAD model substrate ribophorin 332 is delayed, and the overall level of polyubiquitinated cellular proteins is decreased. Defects in the related protein FOXRED1 are a cause of mitochondrial complex I deficiency (MT-C1D), suggesting the FOXRED2 may also play a role in MT-C1D. 宿主：Rbt 用户评论 产品评分 目前评分共0人 产品质量
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