FAM123A蛋白抗体 产品名称 Anti-Amer2 Anti-APC membrane recruitment 2 Antibody 产品介绍
靶标： Amer2 产品别名： 2600011E07Rik； Fam123a； Amer2； APC membrane recruitment 2； APC membrane recruitment 2； APC membrane recruitment protein 2； family with sequence similarity 123, member A； protein FAM123A； FAM123A蛋白； 背景信息： Amer2 (APC membrane recruitment 2; FAM123A) is a direct interaction partner of adenomatous polyposis coli (APC), related to the tumor suppressor Amer1/WTX. FAM123A interacts with APC via two domains that bind the Armadillo repeats of APC. These domains are conserved in the related proteins Amer1/WTX (Wilms tumor gene on the X-chromosome; FAM123B), which acts as a negative regulator of Wnt signaling, and Amer3 (FAM123C). Amer1 is mutated in Wilms tumors and in the inherited disease osteopathia striata congenita with cranial sclerosis. Amer2 negatively regulates Wnt signaling probably by interfering with β-catenin. 宿主：Rbt 用户评论 产品评分 目前评分共0人 产品质量
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