连接介导调节蛋白抗体
 产品名称 Anti-Jmy Anti-junction-mediating and regulatory protein Antibody 产品介绍
靶标： Jmy 产品别名： Jmy； junction-mediating and regulatory protein； junction-mediating and regulatory protein； junction-mediating and -regulatory protein； p300 transcriptional cofactor JMY； 连接介导调节蛋白； 背景信息： function:Cofactor that increases p53/TP53 response via its interaction with p300/EP300. Increases p53/TP53-dependent transcription and apoptosis, suggesting an important role in p53/TP53 stress response such as DNA damage.,induction:By E2F.,PTM:Ubiquitinated by MDM2, leading to its subsequent degradation by the proteasome. In case of DNA damage, the interaction with MDM2 is altered, preventing degradation and allowing interaction with p300/EP300 and its function in p53/TP53 stress response.,similarity:Contains 1 WH2 domain.,subunit:Interacts with p300/EP300, the complex being recruited to activated p53/TP53. Interacts with TTC5., 宿主：Rbt 用户评论 产品评分 目前评分共0人 产品质量
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