重组亮氨酸拉链抑癌蛋白2
产品名称 Recombinant LZTS2 Recombinant leucine zipper tumor suppressor 2 protein 产品介绍
基因名: LZTS2 产品别名: LAPSER1; LZTS2; leucine zipper tumor suppressor 2; leucine zipper tumor suppressor 2; leucine zipper putative tumor suppressor 2; leucine zipper, putative tumor suppressor 2; protein LAPSER1; 亮氨酸拉链抑癌蛋白2; 背景信息: LAPSER1 is a member of the LZTS family. Due to its deletion in multiple cancers, including prostate tumors, LAPSER1 is purported to be a tumor suppressor. In cancer cell lines, the overexpression of LAPSER1 can lead to growth inhibition and colony-forming efficiency. LAPSER1 is highly expressed in testis and prostate, but can be detected at lower levels in spleen, thymus, uterus, small intestine and colon. LAPSER1 colocalizes with ?tubulin, MKLP-1 and p80 katanin. LAPSER1 is involved in cytokinesis. The disruption of LAPSER1, which is accompanied by the mislocalization of p80 katanin, results in malformation of the central spindle. This is a potential impetus for carcinogenesis. 标签:His-tag 用户评论 产品评分 目前评分共0人 产品质量
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