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CAS: 99-92-3
分子式: C8H9NO
分子量: 135.16
沸点: 293℃
熔点: 96-102℃
中文名称: 
4-乙酰基苯胺
对氨基苯基甲基酮
对乙酰苯胺
4'-氨基苯乙酮
对氨基苯乙酮
对氨基苯甲基酮
对氨基乙酰苯
4-氨基苯乙酮
英文名称: 
Acetophenone,4'-amino-
1-(4-Amino-phenyl)-ethanone
p-Aminophenyl methylketone
Ethanone,1-(4-aminophenyl)-
4-Aminoacetophenone
1-(4-aminophenyl)-Ethanone
p-amino-acetophenon
1-(4-aminophenyl)ethanone
4'-aminoacetophenone
4-acetylaniline
4'-amino-acetophenon
1-(4-aminophenyl)-ethanon
p-acetylaniline
p-aminoacetofenonu
p-aminoacetophenone
p-aminoacetylbenzene
usaf ek-631
展开更多英文名
性质描述: 黄色针状结晶。熔点106℃,沸点293-295℃,195-200℃(2kPa)。易溶于热水,溶于醇、醚稀盐酸和稀硫酸,微溶于苯、冷水。有特殊愉快香味。
生产方法: (1)由对硝基苯乙酮还原:将氯化亚锡、浓盐酸放入反应罐,冷却,搅拌加入对硝基苯乙酮。自然升温至90℃时,急冷至85℃,继续冷至室温,搅拌1h,过滤,滤饼加过量氢氧化钠溶液分解复合物。过滤,得对氨基苯乙酮粗品,用稀乙醇时得重结晶可得熔点105-106℃的精品。收率61%用铁粉和氯化钠代替氯化亚锡也可进行还原反应。(2)由乙酰苯胺、乙酐制得乙酰氨基苯乙酮,再水解、中和而得。乙酐、乙酰苯、无水氯化锌混合保持微沸5h,稍冷,倒入浓盐酸,回流水解5h,放置至室温,加入25%氢氧化钠至调节pH为7-8,通入蒸汽赶去苯胺,加脱色炭过滤,减压浓缩,冷却得橙黄色结晶。滤干得粗品。再用水进行重结晶提纯。
用途: 医药喘咳素的中间体。也用于测定钯和维生素B1。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
A800871MACKLIN对氨基苯乙酮99%30元/5g;   55元/25g;   140元/100g;   520元/500g;   2145元/2.5kg;   展开
储存:室温,阴凉
状态:黄色晶体
A800870MACKLIN对氨基苯乙酮试剂级, 98%30元/10g;   69元/50g;   225元/250g;   886元/1kg;   展开
储存:室温,阴凉
A0251TCI4'-Aminoacetophenone>98.0%(T)270元/25G;   750元/100G;   2750元/500G;   展开

基本信息

纯度/分析方法>98.0%(T)
分子式/分子量C8H9NO = 135.17
外观与形状(20℃)固体
Reaxys-RN471493
PubChem物质ID87561908
SDBS (AIST Spectral DB)1502
Merck Index (14)413
MDL编号MFCD00007896

技术规格

AppearanceWhite to Orange to Green powder to crystal
Purity(Nonaqueous Titration)min. 98.0 %
Melting point105.0 to 108.0 ℃

物性(参考值)

熔点107 ℃
沸点293 ℃
水溶性实际上不溶
溶解性(可溶于)乙醚,醇

安全信息

图形或危害标志
信号词警告
危险性说明H302 : 吞咽有害。
H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P270 : 使用本产品时不要进食、饮水或吸烟。
P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。
P301 + P312 + P330 : 如误吞咽:如感觉不适,呼叫急救中心/医生。漱口。

相关法规

RTECS#AM5500000
359582J&K4-Aminoacetophenone99%121元/25G;   303元/100G;   1374元/500G;   展开

基本信息

分子式C8H9NO
分子量135.17
熔点103-107
沸点293
MDL编码MFCD00007896
Beilstein471493
Merck14,413
EINECS 编号202-801-2

安全信息

图形或危害标志
提示语Warning
危险说明H302
H315
H319
H335
防范说明P261
P305+P351+P338
WGK3
RTECSAM5500000
TSCA
A13213Alfa Aesar4'-Aminoacetophenone99%636元/25g;   750元/50g;   3435元/250g;   11500元/1000g;   展开

应用
4'-Aminoacetophenone, is used in pharmaceuticals, medicines and other organic products. It is also used as a reagent for the photometric determination of Ce. As pharmaceutical intemediate or in the determination of palladium and vitaminB1.

备注
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. acids, Incompatible to Acid chlorides, Acid anhydrides, Chloroformates, Strong oxidizing agents, Strong reducing agents. Stable under ordinary conditions.

基本信息

MDL
MFCD00007896

EINECS
202-801-2

分子式
C8H9NO

分子量
135.17

熔点
103-108°

沸点
292-294°

灵敏度
Ambient temperatures.

形态
Crystalline powder

溶解性
It is soluble in hot water, ethanol and ether.

Beilstein
471493

Merck
14,413

GHS危害和防范说明

GHS符号

Hazard Statements
H302-H315-H319-H335
Harmful if swallowed.Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P280h-P305+P351+P338
Wear protective gloves/clothing.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

安全信息

危险类别
22-36/37/38
Harmful if swallowed.Irritating to eyes, respiratory system and skin.

安全等级
26-36/37
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing and gloves.

欧盟危险品标志

RTECS
AM5500000

TSCA

C10309Alfa Aesar4'-Aminoacetophenone99%507元/10g;   627元/25g;   1414元/100g;   6558元/500g;   展开

基本信息

Ref#
10309

MDL
7896

分子式
C8 H9 N O

分子量
135.17

形态
Pale yellow to brown cryst powder

A38002Sigma-Aldrich4′-Aminoacetophenone99%384.38元/25 G;   912.23元/100 G;   展开

基本信息

线性分子式H2NC6H4COCH3
分子量135.16
Beilstein471493
EC 号202-801-2
MDL编号MFCD00007896
PubChem化学物质编号24890814
NACRESNA.22

产品性质

质量水平200
测定99%
bp293 ℃ (lit.)
mp103-107 ℃ (lit.)
SMILES stringCC(=O)c1ccc(N)cc1
InChI1S/C8H9NO/c1-6(10)7-2-4-8(9)5-3-7/h2-5H,9H2,1H3
InChI keyGPRYKVSEZCQIHD-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H302
预防措施声明P301 + P312 + P330
危险分类Acute Tox. 4 Oral
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Faceshields, Gloves
PHR1747Supelco4′-AminoacetophenonePharmaceutical Secondary Standard; Certified Reference Material1940.49元/200 MG;   展开

产品说明

一般描述

4′-Aminoacetophenone, commonly known as Clenbuterol Impurity D, is a related compound of sympathomimetic amine drug clenbuterol. Clenbuterol belongs to a group of compounds referred to as β-2-agonists and is generally used in the treatment of asthma.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

应用

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
4′-Aminoacetophenone may be used as a pharmaceutical reference standard for the determination of the analyte in bulk drug and pharmaceutical formulations by high performance liquid chromatography.

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAC2233 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

基本信息

线性分子式H2NC6H4COCH3
分子量135.16
Beilstein471493
EC 号202-801-2
MDL编号MFCD00007896
PubChem化学物质编号329823592
NACRESNA.24

产品性质

质量水平300
等级certified reference material
pharmaceutical secondary standard
CofAcurrent certificate can be downloaded
包装pkg of 200 mg
technique(s)HPLC: suitable
gas chromatography (GC): suitable
bp293 ℃ (lit.)
mp103-107 ℃ (lit.)
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-30℃
SMILES stringCC(=O)c1ccc(N)cc1
InChI1S/C8H9NO/c1-6(10)7-2-4-8(9)5-3-7/h2-5H,9H2,1H3
InChI keyGPRYKVSEZCQIHD-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H302
预防措施声明P301 + P312 + P330
危险分类Acute Tox. 4 Oral
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
928620Amethyst4-Aminoacetophenone99%, 用于合成96元/25G;   241元/100G;   1017元/500G;   展开

基本信息

分子式C8H9NO
分子量135.17
熔点103-107
沸点293
MDL编码MFCD00007896
Beilstein471493
Merck14,413
EINECS 编号202-801-2

安全信息

图形或危害标志
提示语Warning
危险说明H302
H315
H319
H335
防范说明P261
P305+P351+P338
WGK3
RTECSAM5500000
TSCA
009865Fluorochem4'-Aminoacetophenone98%220元/1g;   264元/25g;   616元/100g;   1980元/500g;   展开

基本信息

CAS Number99-92-3
MDL NumberMFCD00007896
Boiling Point293℃
Melting Point105-107℃
Density0.77

安全信息

图形或危害标志
危险性说明 H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H332: Harmful if inhaled.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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