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CAS: 99-40-1
分子式: C8H7ClO3
分子量: 186.59
熔点: 174-176 °C(lit.)
中文名称: 
氯乙酰儿茶酚
3,4-二羟基-α-氯代苯乙酮
2-氯-3',4'-二羟基苯乙酮
3,4-二羟基-ω-氯代苯乙酮
3,4-二羟基苯酰甲基氯
3,4-二羟基-2'-氯苯乙酮
英文名称: 
Chloracetyl catechol
2-Chloro-1-(3,4-dihydroxyphenyl)ethanone
3,4-Dihydroxyphenacyl chloride
3',4'-dihydroxy-2-chloroacetophenone
2-Chloro-3',4'-dihydroxyacetophenone
4-(Chloroacetyl)catechol
à-Chloro-3,4-dihydroxyacetophenone
4-(Chloroacetyl)-1,2-dihydroxybenzene
4-(Chloroacetyl)pyrocatechol
性质描述: 结晶体。熔点173℃。
生产方法: 将儿茶酚和氯乙酸加入干燥的反应锅内,升温至60℃,搅拌,85-90℃保温0.5h。冷至65℃以下,加入三氯氧磷,60-70℃反应4h,70-80℃反应4h,待反应物稠厚搅拌困难时,加水,升温,90-100℃水解0.5h。冷却结晶,冷至10℃以下,甩滤,固体物用水洗至中性,得2-氯-3',4'-二羟基苯乙酮。
用途: 止血药安络血、拟肾上腺素药物喘息灵等的中间体。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
C917396MACKLIN2-氯-3',4'-二羟基苯乙酮99%89元/25g;   253元/100g;   1196元/500g;   展开
储存:2~8°C
状态:灰色或奶油色到棕色或紫色粉末
C806290MACKLIN2-氯-3',4'-二羟基苯乙酮≥97.0%27元/5g;   53元/25g;   176元/100g;   850元/500g;   4122元/2.5kg;   展开
储存:2~8°C
状态:灰色到棕色粉末
C0156TCI4-(Chloroacetyl)catechol>98.0%(T)(HPLC)520元/25G;   展开

基本信息

纯度/分析方法>98.0%(T)(HPLC)
分子式/分子量C8H7ClO3 = 186.59
外观与形状(20℃)固体
储存在惰性气体下存放于惰性气体之中
应避免的情况湿气 (分解)
Reaxys-RN2092660
PubChem物质ID87565331
SDBS (AIST Spectral DB)1013
MDL编号MFCD00002200

技术规格

AppearanceLight yellow to Brown powder to crystal
Purity(HPLC)min. 98.0 area%
Purity(Neutralization titration)min. 98.0 %

物性(参考值)

熔点173 ℃

安全信息

图形或危害标志
信号词警告
危险性说明H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
防范说明P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。
510939J&K2-Chloro-3',4'-dihydroxyacetophenone97%470元/25G;   1549元/100G;   展开

基本信息

分子式C8H7ClO3
分子量186.59
熔点174-176
MDL编码MFCD00002200
Beilstein2092660
EINECS 编号202-754-8

安全信息

图形或危害标志
提示语Warning
危险说明H315
H319
H335
防范说明P261
P305+P351+P338
WGK3
TSCA
B23496Alfa Aesar2-Chloro-3',4'-dihydroxyacetophenone97%1268元/25g;   4106元/100g;   13376元/500g;   展开

应用
2-Chloro-3',4'-dihydroxyacetophenone is used as a styptic adrenobazone, quasi adrenaline drug gasp spirit of intermediates.

备注
Store in a cool, dry conditions, in well sealed conditions. Store away from oxidizing agents.

基本信息

MDL
MFCD00002200

EINECS
202-754-8

分子式
C8H7ClO3

分子量
186.59

熔点
172-176°

灵敏度
Ambient temperatures.

形态
Powder

溶解性
Soluble in DMSO, methanol.

Beilstein
2092660

GHS危害和防范说明

GHS符号

Hazard Statements
H315-H319-H335
Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
36/37/38
Irritating to eyes, respiratory system and skin.

安全等级
26-37
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

TSCA

Y0000682Noradrenaline impurity EEuropean Pharmacopoeia (EP) Reference Standard1572.27元/ ;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 10 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

线性分子式(HO)2C6H3COCH2Cl
分子量186.59
MDL编号MFCD00002200
PubChem化学物质编号329831093
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
mp174-176 ℃ (lit.)
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringOc1ccc(cc1O)C(=O)CCl
InChI1S/C8H7ClO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,10-11H,4H2
InChI keyLWTJEJCZJFZKEL-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H319 - H335
预防措施声明P302 + P352 - P305 + P351 + P338
危险分类Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
C34405Sigma-Aldrich2-Chloro-3′,4′-dihydroxyacetophenone97%840.92元/25 G;   展开

基本信息

线性分子式(HO)2C6H3COCH2Cl
分子量186.59
EC 号202-754-8
MDL编号MFCD00002200
PubChem化学物质编号24892617
NACRESNA.22

产品性质

质量水平100
测定97%
mp174-176 ℃ (lit.)
SMILES stringOc1ccc(cc1O)C(=O)CCl
InChI1S/C8H7ClO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,10-11H,4H2
InChI keyLWTJEJCZJFZKEL-UHFFFAOYSA-N
Gene Informationhuman ... PTPN6(5777)

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H319 - H335
预防措施声明P302 + P352 - P305 + P351 + P338
危险分类Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
209994Fluorochem2-Chloro-1-(3,4-dihydroxyphenyl)ethanone95%220元/10g;   220元/1g;   374元/25g;   1232元/100g;   12056元/1kg;   展开

基本信息

CAS Number99-40-1
MDL NumberMFCD00002200

安全信息

图形或危害标志
危险性说明 H314: Causes severe skin burns and eye damage.
防范说明 P260: Do not breathe .
P264: Wash hands thoroughly after handling.
P280: Wear .
P301 + P330 + P331: IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303 + P361 + P353: IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P310: Immediately call a POISON CENTER or doctor/physician.
P321: Specific treatment (see . on this label).
P363: Wash contaminated clothing before reuse.
P405: Store locked up.
P501: Dispose of contents/container to local regulations.
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